Laboratory Services

Bone Alkaline Phosphatase, Serum

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Updated Test Information:

Test Description
Bone Alkaline Phosphatase, Serum
Synonym(s)

Alkaline Phosphatase, Bone; BAP, Phosphatase, Skeletal Alkaline Phosphatase

Test ID
BAP
General Information

Diagnosis and assessment of severity of metabolic bone disease including Paget disease, osteomalacia, and other states of high bone turnover.


Monitoring efficacy of antiresorptive therapies including postmenopausal osteoporosis treatment


The assay is not intended as a screening test for osteoporosis.


Measurements of bone turnover markers are not useful for the diagnosis of osteoporosis; diagnosis of osteoporosis should be made based on bone density.

Container Type

SST

Specimen Type

Serum

Alternate Specimen Type

Red top

Specimen Requirements

0.6 mL

Specimen Collection / Processing Instructions

Centrifuge and aliquot serum into plastic vial

Minimum Sample Volume

0.5 mL

Stability

Refrigerated (preferred) 14 days
Frozen 90 days
Ambient 7  days

Unacceptable Specimen Conditions

Gross hemolysis

Methodology

Immunoenzymatic Assay

Estimated TAT

2 to 3 days

Testing Schedule

Monday through Sunday

Retention

14 days

CPT Code(s)

84080

Reference Range

Males


<2 years: 25-221 mcg/L


2-9 years: 27-148 mcg/L


10-13 years: 35-169 mcg/L


14-17 years: 13-111 mcg/L


Adults: < or =20 mcg/L


 


Females


<2 years: 28-187 mcg/L


2-9 years: 31-152 mcg/L


10-13 years: 19-177 mcg/L


14-17 years: 7-41 mcg/L


Adults


Premenopausal: < or =14 mcg/L


Postmenopausal: < or =22 mcg/L

Performing Lab

Mayo

LOINC Code(s)

17838-4