Laboratory Services
C4 Complement
Print this pageUpdated Test Information:
| Test Description |
C4 Complement
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|---|---|---|
| Synonym(s) |
C4, Complement C4
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| Test ID |
C4C
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| General Information |
Quantitation of C4 is used to detect individuals with inborn deficiency of this factor or those with immunologic disease in whom hypercatabolism of complement causes reduced levels. These diseases include lupus erythematosus, serum sickness, certain glomerulonephritides, chronic active hepatitis, and others.
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| Specimen Type |
Serum
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| Specimen Requirements |
SST
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| Alternate Specimen Type |
Red, Li-heparin plasma
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| Specimen Collection / Processing Instructions |
SST - Separate serum or plasma from cells within 45 minutes of collection. If a red-top tube or green-top tube is used, transfer separated serum or plasma to a plastic transport tube.
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| Minimum Sample Volume |
1 mL
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| Pediatric Min. Volume (if applicable) |
500 uL
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| Additional Processing Details |
Separate serum or plasma from cells within 45 minutes of collection. If a red-top tube or green-top tube is used, transfer separated serum or plasma to a plastic transport tube.
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| Stability |
2 days at 20-25˚C
8 days at 4-8˚C 3 months at -20˚C |
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| Limitations |
Excessive lipemia (>250 mg/dL) and rheumatoid factors (>200 IU/mL) significantly increase the apparent C4 concentration.
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| Methodology |
Immunoturbidimetric
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| Estimated TAT |
0-2 days
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| Testing Schedule |
Monday-Saturday
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| CPT Code(s) |
86160
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| Reference Range |
10-40 mg/dL
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| Performing Lab |
Incyte Diagnostics
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| LOINC Code(s) |
4498-2
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