Laboratory Services

Copeptin proAVP, Plasma

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Updated Test Information:

Test Description
Copeptin proAVP, Plasma
Test ID
CPAVP
General Information

Investigating the differential diagnosis for patients with water balance disorders, including diabetes insipidus, in conjunction with osmolality and hydration status


May aid in the evaluation of cardiovascular disease in conjunction with other cardiac markers

Container Type

Lavender top

Specimen Type

Plasma

Specimen Requirements

0.5 mL

Specimen Collection / Processing Instructions

Centrifuge and aliquot plasma into plastic vial. Do not submit in original tube.

Minimum Sample Volume

0.3 mL

Stability

Refrigerated (preferred) 7 days
Frozen 30 days
Ambient 7 days

Unacceptable Specimen Conditions

Gross hemolysis

Methodology

Immunofluorescent Assay (IFA)

Estimated TAT

2 to 3 days

Testing Schedule

Monday through Saturday

Retention

2 weeks

CPT Code(s)

84588

Reference Range

Non-water deprived, non-fasting adults*: <13.1 pmol/L


Water deprived, fasting adults**: <15.2 pmol/L


Non-water deprived, non-fasting pediatric patients***: <14.5 pmol/L


Note:


*Keller T, Tzikas S, Zeller T, et al: Copeptin improves early diagnosis of acute myocardial infarction. J Am Coll Cardiol. 2010 May 11;55[19]:2096-2106. doi: 10.1016/j.jacc.2010.01.029


**In-house Mayo study.


***Du JM, Sang G, Jiang CM, He XJ, Han Y: Relationship between plasma copeptin levels and complications of community-acquired pneumonia in preschool children. Peptides. 2013 Jul;45:61-65. doi: 10.1016/j.peptides.2013.04.015

STAT Orderable (Y/N)

No

Performing Lab

Mayo

LOINC Code(s)

78987-5