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Cryoglobulins

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Updated Test Information:

Test Description
Cryoglobulins
Synonym(s)

UOW1135
Test ID
CRYOG
General Information

Use this mnemonic when only Cryoglobulin requested.


This assay detects the presence of a cryoglobulin, and if present, provides a semi quantitative estimate of the amount. Cryoglobulins are associated with a variety of clinical conditions including: myeloma, Waldenstrom's macroglobulinemia, chronic lymphocytic leukemia, rheumatoid arthritis, Sjogren's syndrome, mixed essential cryoglobulinemia, systemic lupus erythematosus, infectious mononucleosis, cytomegalovirus infections, acute viral hepatitis, primary biliary cirrhosis, post streptococcal glomerulonephritis, infective endocarditis, leprosy, kalaazar, and tropical splenomegaly syndrome.
Container Type

15 mL blood in Red Top tubes.
Specimen Type

Blood
Specimen Requirements

Serum
Specimen Collection / Processing Instructions

Sample MUST be kept at 37c from collection through placing into centrifuge



  1. Immediately after collection place tube in 37c water bath or warming plate to clot for 1-2 hours to prevent CRYOGLOBULINS from being trapped in clot

  2. After clotting process is complete, centrifuge and aliquot serum while the sample is still warm

  3. Refrigerate the aliquoted serum
Minimum Sample Volume

3 mL serum
Stability

Refrigerate aliquoted serum. DO NOT FREEZE.
Department (code)

Immunology (IMM)
Methodology

Precipitation (Passive precipitation at refrigerator temperature, that is reversible when warmed to 37°C)
Estimated TAT

11 Days
Testing Schedule

Monday - Friday
Test Includes

CRYO            -    Cryoglobulin, Serum at 3 day
CRYO10      -   Cryoglobulin, Serum at 10 day
CRYMTH    -   Cryoglobulins Method 
CPT Code(s)

82595
STAT Orderable (Y/N)

No
Performing Lab

UW
LOINC Code(s)