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Cytomegalovirus (CMV) Antibodies, IgG, Serum

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Updated Test Information:

Test Description
Cytomegalovirus (CMV) Antibodies, IgG, Serum
Synonym(s)

CMV (Cytomegalovirus) Antibody; Torch IgG
Test ID
CMVG
General Information

Useful for determining whether a patient (especially transplant recipients, organ and blood donors) has had a recent infection or previous exposure to cytomegalovirus
Specimen Type

Serum
Specimen Requirements

  • Preferred: Serum Gel

  • Acceptable: Red Top
Minimum Sample Volume

0.4 mL
Stability

  • Refrigerated (preferred): 14 days

  • Frozen: 14 days
Unacceptable Specimen Conditions

  • Gross hemolysis

  • Gross lipemia

  • Gross icterus

  • Heat-inactivated specimen
Limitations

  • Sera drawn very early during the acute stage of infection may have undetectable levels of cytomegalovirus (CMV) IgG. The CMV IgG assay should not be used alone to diagnose CMV infection. Results should be considered in conjunction with clinical presentation, patient history, and other laboratory findings. In cases of suspected disease, submit a second specimen for testing in 10 to 14 days

  • The performance characteristics of this assay have not been evaluated in immunosuppressed or organ transplant recipients and have not been established for cord blood or for testing of neonates

  • Immune complexes or other immunoglobulin aggregates present in patient samples may cause increased nonspecific binding and produce false-positive results

  • Potential cross-reactivity for CMV with human chorionic gonadotropin, HIV IgG, multiple myeloma IgG, rheumatoid factor IgM, and Toxoplasma gondii IgG have not be ruled out
Methodology

Multiplex Flow Immunoassay (MFI)
Estimated TAT

1-3 days
Testing Schedule

Monday-Saturday
Retention

14 days
CPT Code(s)

86644
Reference Range

Negative
Performing Lab

Mayo
LOINC Code(s)

13949-3
Additional Information