Laboratory Services

Luteinizing Hormone (LH), Pediatrics, Serum

Print this page

Updated Test Information:

Test Description
Luteinizing Hormone (LH), Pediatrics, Serum
Synonym(s)

Third Generation LH assay; Ultrasensitive LH assay; Lutropin

Test ID
LHPED
General Information

Useful for diagnosis of precocious puberty and delayed puberty in children

Specimen Type

Serum

Specimen Requirements

  • Preferred: Red Top

  • Acceptable: Serum Gel (SST)

Specimen Collection / Processing Instructions

  • Red-top tubes should be centrifuged and the serum transferred to an aliquot vial within 2 hours of collection

  • Serum gel tubes should be centrifuged within 2 hours of collection.

Minimum Sample Volume

0.13 mL

Stability

  • Refrigerated (preferred): 14 days

  • Frozen: 90 days

Unacceptable Specimen Conditions

  • Gross hemolysis

  • Gross lipemia

  • Gross icterus

Limitations

  • No clinically significant cross-reactivity has been demonstrated with follicle-stimulating hormone, human chorionic gonadotropin, free alpha subunit of pituitary glycoprotein hormones, or free beta subunit of luteinizing hormone. Cross-reactivity with thyroid-stimulating hormone (TSH) (<5%) might be observed at TSH concentrations of 500 mIU/L

  • Some patients who have been exposed to animal antigens, either in the environment or as part of treatment or imaging procedures, may have circulating anti-animal antibodies present. These antibodies may interfere with the assay reagents to produce unreliable results

Methodology

Chemiluminescent Immunoassay (CIA)

Estimated TAT

2-9 days

Testing Schedule

Friday

Retention

3 months

CPT Code(s)

83002

Reference Range

 

Age (years) Males (IU/L) Females (IU/L)
< 1 <0.2 - 5.0 <0.2 - 18.3
1 - 8 <0.2 - 5.0 <0.2 - 0.3
9 - 10 <0.2 - 3.6 <0.2 - 4.8
11 - 13 0.1 - 5.7 <0.2 - 11.7
14 - 17 0.8 - 8.7 <0.2 - 16.7
Tanner Stage*  
Stage I (1-8 years) <0.2 - 5.0 <0.2 - 0.3
Stage II 0.03 - 3.7 <0.2 - 4.1
Stage III 0.09 - 4.2 0.6 - 7.2
Stage IV-V 1.3 - 9.8 0.9 - 13.3

*Puberty onset (transition from Tanner stage I to Tanner stage II) occurs for girls at a median age of 10.5 (+/- 2)
years. There is evidence that it may occur up to 1 year earlier in obese girls and in African-American girls.
Progression through Tanner stages is variable. Tanner stage V (adult) should be reached by age 18.

*Puberty onset (transition from Tanner stage I to Tanner stage II) occurs for boys at a median age of 11.5 (+/- 2)
years. For boys there is no proven relationship between puberty onset and body weight or ethnic origin. Progression through Tanner stages is variable. Tanner stage V (adult) should be reached by age 18.

Performing Lab

Mayo

LOINC Code(s)

83103-2

Additional Information