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Nuclear Magnetic Resonance Lipoprotein Profile, Serum

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Updated Test Information:

Test Description
Nuclear Magnetic Resonance Lipoprotein Profile, Serum
Synonym(s)

HDL particle number; HDL particles; LDL Cholesterol; LDL particle number; LDL particles; Lipoprotein particles; NMR; NMRLP; NMR profile; Nuclear magnetic resonance
Test ID
NMRLP
General Information

Useful for:



  • Assessment and management of a patient's risk for atherosclerotic cardiovascular disease

  • Identifying residual risk that may be present in some patients on cholesterol targeting treatment
Specimen Type

Serum
Specimen Requirements

Red Top
Specimen Collection / Processing Instructions

  • Patient Preparation:

    • Fasting overnight (12-14 hours) is required. On night before examination, evening meal should be eaten before 6 p.m. and should contain no fatty foods

    • Patient must not consume any alcohol for 24 hours before the specimen is collected



  • Collection Instructions:

    • Allow isopropyl alcohol (from phlebotomy site prep) to dry thoroughly before venipuncture

    • Centrifuge and aliquot serum
Minimum Sample Volume

1 mL
Stability

  • Refrigerated (preferred): 7 days

  • Frozen: 14 days

  • Ambient: 8 hours
Unacceptable Specimen Conditions

  • Gross hemolysis

  • Gross lipemia

  • Gross icterus
Limitations

Failure to follow specimen collection requirements may prevent measurable results
Methodology

Nuclear Magnetic Resonance (NMR)
Estimated TAT

2-7 days
Testing Schedule

Tuesday and  Friday
Test Includes

  • LDL Particles

  • HDL Particles

  • LDL Cholesterol (NMR)
Retention

7 days
CPT Code(s)

83704
Reference Range
Gender HDL Particles (mcmol/L)
Male > 30
Female > 35
Range LDL Particles (nmol/L) LDL Cholesterol (NMR): (mg/dL)
Desirable < 1000 < 100
Above Desirable 1000 - 1299 100 - 129
Borderline High 1300 - 1599 130 - 159
High 1600 - 1999 160 - 189
Very High ≥ 2000 ≥ 190


Reference values have not been established for patients who are <18 years of age.
Performing Lab

Mayo
LOINC Code(s)

54434-6, 49748-7, 2089-1
Additional Information