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Pediatric Allergy Panel, Reflex to Components

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Updated Test Information:

Test Description
Pediatric Allergy Panel, Reflex to Components
Synonym(s)

Childhood, Profile
Test ID
CHILDR
General Information

An allergen is a type of antigen that initiates an immune response. After this initiation, also called sensitization, an allergic individual will produce IgE against that allergen. Specific IgE can be used to determine allergen sensitization, potential anaphylaxis response, and aid in disease management. Testing the individual components of an allergen, referred to as component resolved diagnosis (CRD), improves the predictive value for determining severity of allergen sensitization. Assay results should be used in conjunction with clinical findings and other serological tests.
Specimen Type

Serum
Specimen Requirements

Tiger
Alternate Specimen Type

Plasma (Na-Heparin or EDTA)
Minimum Sample Volume

4 mL
Pediatric Min. Volume (if applicable)

2 mL
Additional Processing Details

Preferred: Centrifuge serum samples (SST, Red Top) within 2 hours of collection.
Alternate: if centrifuging is not possible, uncentrifuged serum samples (SST, Red Top) are acceptable.
Caution: Add-on testing may not be possible on serum samples that are received uncentrifuged. Serum/plasma samples are not to be repeatedly frozen and thawed, since this can cause analyte deterioration. They are to be thawed only once.
Stability

Stored at 2-8˚C: 7 Days
Specimens may be kept at controlled room temperature for shipping purposes only. Otherwise, they should be stored at 2-8˚C if assayed within 7 days or -20˚C for longer-term storage.
Methodology

Fluorescent enzyme immunoassay (FEIA)
Estimated TAT

2-5 days
Testing Schedule

Monday-Saturday, alternating days
Test Includes

Alternaria alternate, Cat Dander, Cladosporium herbarum, Cockroach (German), Cod (fish), D. farina, D. pteronyssinus, Dog Dander, Egg White, Milk (Cow), Mouse Urine, Peanut, Shrimp, Soybean, Walnut (Nut), Wheat, Total IgE
CPT Code(s)

86003x16
82785
Reference Range File INCYTE Allergy Reference Values
Reflex Conditions

If Milk IgE is positive, a Milk Component Panel will be performed. The Milk Component Panel includes: Alpha-lactalbumin IgE, Beta-lactoglobulin IgE, and Casein IgE.
If Egg White IgE is positive, an Egg White Component Panel will be performed. The Egg White Component Panel includes: Ovalbumin IgE and Ovomucoid IgE.
If Peanut IgE is positive, a Peanut Component Panel will be performed. The Peanut Component Panel includes: Ara h 1, Ara h 2, Ara h 3, Ara h 6, Ara h 8, and Ara h 9.
Performing Lab

Incyte Diagnostics
LOINC Code(s)

6833-8, 6098-8, 6182-2, 6106-9, 6206-7, 6248-9, 7258-7, 6246-3, 6273-7, 6082-2, 6276-0, 30170-5, 6075-6, 6020-2, 6095-4, 6096-2, 19113-0