Laboratory Services
Protein C Activity
Print this pageUpdated Test Information:
Test Description |
Protein C Activity
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Synonym(s) |
UOW883, Protein C Level |
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Test ID |
PCCLOT
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General Information |
Protein C Activity is a quntitative determination of the functional protein C level in plasma by the synthetic chromogenic substrate method. This assay is insensitive to hemoglobin (up to 2 g/l), bilirubin (up to 200 mg/l) and triglycerides (up to 4 g/l). PIVKA protein C (PIVKA: protein induced by vitamin K antagonists) present in the plasma of patients receiving oral anticoagulant therapy may be measured by the colorimetric method. Patients on warfarin therapy may see decrease in protein C activity because of the vitamin K antagonistic effect of the drug. Protein C is a vitamin K dependent factor. The presence of aprotinin in the plasma may result in an underestimation of the protein C level. Outside clients should fill and submit Coagulation Patient Clinical History Form |
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Container Type |
3 or 5 mL Blue Top (CITRATE) tube |
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Specimen Type |
Plasma |
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Specimen Collection / Processing Instructions |
Centrifuge for 10 minutes, remove plasma & re-spin plasma for another 10 minutes. Decant & Freeze plasma (minimum 1.0 mL) @ -20°C to -80°C. Send frozen on dry The Laboratory MUST process specimen, within 4 hrs of blood collection. |
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Department (code) |
Coagulation |
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Methodology |
Stago STA Stachrom Protein C |
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Testing Schedule |
Monday, Thursday |
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CPT Code(s) |
85303 |
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Reference Range |
Units: % Male/Female 0-29d 20-150 1m-2m 21-150 3m-5m 28-150 6m-11m 37-150 1y-5y 40-150 6y-9y 45-150 10y - 65-150 Effective date: 07/01/2004 Elevated Protein C is not associated with thrombosis or bleeding. |
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STAT Orderable (Y/N) |
No |
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Performing Lab |
UW |
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LOINC Code(s) | ||
Collection File | View/Download File |