Laboratory Services

Riboflavin (Vitamin B2), P

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Updated Test Information:

Test Description
Riboflavin (Vitamin B2), P
Synonym(s)

Riboflavin, Vitamin B2

Test ID
VITB2
General Information

Useful for evaluation of individuals who present the signs of ariboflavinosis

Container Type

Preferred: Green top (sodium or lithium heparin)
Acceptable: Light-green top (sodium or lithium heparin plasma gel)
Submission Container/Tube: Sarstedt 5 mL Aliquot Tube (Amber) (T915)

Specimen Type

Plasma Heparin

Specimen Requirements

2mL

Specimen Collection / Processing Instructions

Centrifuge within 2 hours of collection and aliquot plasma into amber vial.

Minimum Sample Volume

0.5 mL

Required Information

Patient Preparation: Fasting-overnight (12-14 hours) (infants-collect specimen prior to next feeding)

Stability

Refrigerated: 28 Days (LIGHT PROTECTED). Ship specimen in amber vial to protect from light.


Frozen: 28 Days (LIGHT PROTECTED)


Ambient: 72 Hours (LIGHT PROTECTED)

Unacceptable Specimen Conditions

Gross hemolysis, Gross lipemia

Methodology

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)


Portions of this test are covered by patents held by Quest Diagnostics

Estimated TAT

3-6 Days

Testing Schedule

Monday, Wednesday, Friday

Retention

14 Days

CPT Code(s)

84252

Reference Range

1-19 mcg/L

STAT Orderable (Y/N)

No

Performing Lab

Mayo

LOINC Code(s)

Test Id                    Test Order Name                                   Order LOINC Value
VITB2                     Riboflavin (Vitamin B2), P                2924-9



Result Id              Test Result Name                                 Result LOINC Value
61637                   Riboflavin (Vitamin B2), P               2924-9

Additional Information

Low concentrations in the blood plasma are indicative of nutritional deficiency. Concentrations below 1 mcg/L are considered significantly diminished. Marginally low levels probably represent nutritional deficiency that should be corrected.

Testing of nonfasting specimens or the use of dietary vitamin B2 supplementation can result in elevated plasma vitamin B2 concentrations.